TIADINIL SOLUTION
TIADINIL
CAS: 223580-51-6
Molecular Formula: C11H10ClN3OS
TIADINIL SOLUTION - Names and Identifiers
TIADINIL SOLUTION - Physico-chemical Properties
| Molecular Formula | C11H10ClN3OS |
| Molar Mass | 267.73 |
| Density | 1.418±0.06 g/cm3(Predicted) |
| Melting Point | 111-113°C |
| Appearance | neat |
| pKa | 10.52±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Physical and Chemical Properties | The pure chemical product is beige solid, m.p.112.2 ℃, relative density 1.47 (20 ℃), vapor pressure 1.03 × 10-6Pa, partition coefficient 3.68 (25 ℃), solubility 13.2mg/L in water at 20 ℃. |
| Use | The use of novel systemic fungicide, absorption through the root of the rapid conduction to other parts. The agent itself has poor inhibitory activity against pathogens, and can induce the production of disease resistance genes by preventing the mycelia of pathogens from invading adjacent healthy cells. It is suitable for water use, and has long effective period. It has good control effect on leaf rice blast and Panicle rice blast, especially for rice seedling box. In the early stage of the disease, the drug effect is especially good. Prevention and Control of leaf rice blast, water dissemination, the recommended dosage of 1.8kg active ingredient/hm2, before the onset of 7 ~ 20d use, medication is not more than two times. With Fipronil, imidacloprid mixture can control rice blast, Weevil, leaf hopper, planthopper and other pests. |
TIADINIL SOLUTION - Risk and Safety
| Risk Codes | R20 - Harmful by inhalation R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| WGK Germany | 3 |
| Toxicity | 大鼠急性经口 LD50>61500mg/kg，大鼠急性经皮 LD50>2000mg/kg，大鼠急性吸入 LC50>7mg/L。对兔眼睛无刺激作用。动物试验无致畸性，对大鼠无繁殖毒性，对小鼠无变异性。家蚕 LD50>400mg/kg，蜜蜂成虫 LD50>1000mg/kg。 |
TIADINIL SOLUTION - Upstream Downstream Industry
| Raw Materials | Thionyl chloride Ethyl acetoacetate 2-Mercapto-5-methyl-1,3,4-thiadiazole (-)-MENTHYL CHLOROFORMATE |
TIADINIL SOLUTION - Nature
| storage conditions | Sealed in dry,2-8°C |
| morphology | neat |
| acidity coefficient (pKa) | 10.52±0.70(Predicted) |
Last Update：2024-04-10 22:29:15
TIADINIL SOLUTION - Uses and synthesis methods
Toxicity
rat acute oral LD50>61500mg/kg, rat acute percutaneous LD50>2000mg/kg, rat acute inhalation LC50>7mg/L. No irritation to rabbit eyes. Animal experiments have no teratogenicity, no reproductive toxicity to rats, and no variability to mice. Silkworm LD50>400mg/kg, bee adult LD50>1000mg/kg.
biological activity
Tiadinil is a plant activator of system acquired resistance, which can promote the production of plant volatiles induced by herbivores and is a fungicide.
production method
After condensing ethyl acetoacetate and hydrazinyl formate in ethanol, then close the ring with dichlorosulfoxide to prepare 4-methyl-1, 2, 3-thiadiazol-5-formate, After hydrolyzing it into the corresponding acid, chlorinated with dichlorosulfoxide to prepare the corresponding acid chloride, and then reacted with 3-chloro-4-methylaniline under the action of the acid binding agent, you can make thioamide.
Last Update：2024-04-10 22:39:43
TIADINIL SOLUTION - Security information
| WGK Germany | 3 |
Last Update：2024-04-10 22:29:15
TIADINIL SOLUTION - Reference Information
| toxicity | rat acute oral LD50>61500mg/kg, rat acute percutaneous LD50>2000mg/kg, rat acute inhalation LC50>7mg/l. No irritation to rabbit eyes. Animal experiments have no teratogenicity, no reproductive toxicity to rats, and no variability to mice. Silkworm LD50>400mg/kg, bee adult LD50>1000mg/kg. |
| biological activity | Tiadinil is a plant activator of system acquired resistance, which can promote the production of plant volatiles induced by herbivores and is a fungicide. |
| chemical properties | pure product is beige solid, m.p.112.2 ℃, relative density 1.47 (20 ℃), vapor pressure 1.03 × 10-6Pa, partition coefficient 3.68 (25 ℃), solubility in water at 20 ℃ 13.2mg/L. |
| use | the novel systemic fungicide is rapidly transmitted to other parts through root absorption. The drug itself has poor inhibitory activity on bacteria. It can prevent the mycelium from invading neighboring healthy cells and induce the production of disease resistance genes. It is suitable for hydraulic use, has a long duration, and has a good control effect on leaf blast and ear blast, especially suitable for rice seedling boxes. The effect of medication is particularly good in the early stages of the disease. Prevention and control of leaf rice blast, water surface spread, recommended dosage of 1.8kg active ingredient/hm2, use 7~20 days before onset, medication no more than twice. Mixing with fipronil and imidacloprid can control rice blast, weevil, leafhopper, planthopper and other pests. |
| Production method | After condensing ethyl acetoacetate and hydrazinyl formate in ethanol, the ring is then closed with dichlorosulfoxide to prepare 4-methyl -1,2, 3-thiadiazole -5-formate, which is hydrolyzed into the corresponding acid, chlorination of dichlorosulfoxide is used to prepare the corresponding acid chloride, and then it reacts with 3-chloro-4-methylaniline under the action of the acid binding agent to prepare thiacidamide. |
Last Update：2024-04-09 21:54:55
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Product Name: Tiadinil Visit Supplier Webpage Request for quotationCAS: 223580-51-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Tiadinil Request for quotationCAS: 223580-51-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Tiadinil Visit Supplier Webpage Request for quotationCAS: 223580-51-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tiadinil Visit Supplier Webpage Request for quotationCAS: 223580-51-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: Tiadinil Visit Supplier Webpage Request for quotation
CAS: 223580-51-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 223580-51-6
Tel: 18301782025
Email: 3008007409@qq.com
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Raw Materials for TIADINIL SOLUTION